The endocannabinoid system (ECS) is a group of cannabinoid receptors located in the brain and throughout the central and peripheral nervous systems, consisting of neuromodulatory lipids and their receptors. There are two main types of receptors in the ECS, CB1 and CB2. CB1 receptors are primarily located in the central nervous system and brains of mammals, and CB2 are generally found in the peripheral nervous system. There are two main cannabinoids mammals produce- 2AG and Anandamide. Read more by clicking here
We also rated the product based on the type of CBD they used: isolate, full-spectrum decarb, broad-spectrum, or distillate. There’s a lot of debate around what is actually best, but our first decision was to give points to CBD oil that contains a range of cannabinoids. While there are certainly people with good reasons for choosing an isolate, there’s a lot of good evidence that CBD works better in combination with other cannabinoids (this is called the “entourage effect”).
CBD and cannabis have been studied in other specific cancers. A 2013 study published in the journal Chemotherapy studied the effects of synthetic THC against gastric cancer grafts in rodents. Rodents treated with the THC saw a 30 percent reduction in tumor growth over 14 days of treatment when compared to the control. A 2012 Journal of Molecular Medicine study found tumors in mice with laboratory-induced colon cancer shrunk with CBD treatment. A 2013 study published in Molecular Cancer Therapeutics found that CBD triggers cell death in certain lung cancer cell lines, decreasing tumor viability.
With no regulations when it comes to the distribution of CBD hemp-based products, you can never be sure what you are purchasing. This leaves consumers exposed to the side effects of impure hemp oil CBD. Despite these challenges, it is possible to buy the right CBD oil in the market. Several reputable companies have risen to offer reliable, safe and potent CBD products to the market. Read reviews of the top selling CBD oils on our site to get an understanding of what makes them unique in this rapidly growing market so you can make an informed decision. Our goal is to bring CBD to the people while helping them make better decisions every day. You can count on us to provide CBD reviews you can trust. Keep in mind that we recommend only the best CBD brands on the market.
NuLeaf Naturals is headquartered in Colorado, but we ship anywhere in the US. All of our organic CBD oil products will be sent to you via USPS, FedEx, or UPS and should arrive in just 2-3 business days. We offer special pricing options for bulk orders. If you sell health and wellness products and would be interested in promoting medical cannabis oil, consider becoming a wholesale CBD oil partner with us.