For those needing a refresh, CBD or cannabidiol is one of the many compounds, or cannabinoids, found both in cannabis sativa (federally illegal) and industrial hemp (gray area) that has shown preclinical promise in treating anxiety and inflammation. Adding to its therapeutic legitimacy, CBD was recently FDA-approved to be used in an epilepsy drug called Epidiolex making it the first cannabis compound to be federally recognized. Over the last year, CBD’s become the darling of the wellness world, working its way into our juices, facials, creams, and cocktails, purportedly giving people the benefits of cannabis without the THC high. Very chill.
Is it full-spectrum? Full-spectrum is the use of the whole hemp plant vs. an isolate which extracts the CBD from the plant. Using marketing terms like “pure” and “all natural,” isolates are sometimes not hemp at all and synthesized in a lab. While the efficacy of full-spectrum is debated in the scientific community, anecdotes and a study in Israel favor full-spectrum. In addition to potential benefits, there’s another reason you should be buying the whole plant: contamination. Chen notes that isolates are harder to trace back to origin and can be straight-up fake. Overseas lab-made isolates are cheaper than domestic versions, making the potential for contamination high. Utah recently grappled with synthetic CBD when 52 people became sick from an isolate. While isolates can be legitimate (FDA-approved Epiliodex is an isolate), you’re going to have to spend more time researching the brand’s products and practices. Put it this way, if you could get your vitamin C from Sunny D or fresh squeezed OJ, which would you prefer?

But, and there’s always a “but” when it comes to weed in America, unless you’re buying cannabis CBD in a state where weed is recreationally legal or have a medical card in a legalized state, you’re shopping in the unregulated market that is industrial hemp CBD. (Full disclosure: I've worked with restaurants to launch hemp-CBD drinks and am the co-founder of Nice Paper, a site about cannabis.)
Whether you’re purchasing CBD oil or CBD hemp oil for sale, remember that what is written on the bottle – the big 300mg – doesn’t mean that the 300mg is packed with CBD only. It means that the whole bottle is 300mg. It’s important to read the label. When calculating the actual CBD content, you’ll want to remember that the following ground rules apply:
The human body has an endocannabinoid system — a natural system that maintains homeostasis or balance, in the body. The endocannabinoid system has CB1 and CB2 receptors. These are found throughout the body. CB1 receptors are generally located in the central and peripheral nervous system and CB2 receptors are generally found in the brain, immune system, and gastrointestinal system. CBD binds to these receptors creating changes and effects in the body
Others companies use organic, pharmaceutical-grade ethanol to process CBD. The ethanol, which is essentially grain alcohol, is used to remove unneeded toxins and residues from the base hemp plant. This method of extraction is generally considered to be the extraction process that yields the highest amount of cannabinoids among the different refinement processes as well as being considered the safest method of extracting CBD for human consumption.
That’s why, when it comes to purchasing CBD products, you need to know what to look out for before you start browsing. Do you know which companies have a reputation for producing low-quality versus high-quality CBD products? Do you know which lab results you should ask to see? Or which manufacturing certifications point to quality practices being adhered to? Make sure you do before clicking “Add to Cart.”
Edibles begin with a raw or decarb oil as part of the base ingredients. They can be any number of things, from chocolate to hard candy, gummies, even teas and coffee. This is a way to “sneak” cannabinoids in a fun way and can be delicious (the Koi gummies are so good!) but they are not an extremely cost-effective way to allow cannabinoids to boost your overall health and well being on a daily basis.

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Are they open about third party tests and willing to share the results? When in doubt, ask for multiple lab tests including from the farm and a third-party lab. They’ll list out contaminants, solvents, and the percentage of cannabinoids. According to White, “brands should be happy to share their results as they’ve invested in those tests. If they aren’t transparent, it’s suspect.” Brands like RITUAL, Care by Design, Humbodlt Apothecary and Kinslips have all gone through rigorous testing standards as they are cannabis derived. Since you can’t travel across state lines with cannabis CBD, industrial hemp CBD brands that have well-sourced farms and openly share tests include Lily CBD, Rosebud, Honey Pot Supply, and Soul Addict.
I would recommend always going with a full spectrum oil. Some people say to use nothing but pure 100% CBD, but if you do a little research you’ll see that most doctors will say that the full-spectrum products with terpenes etc are much more potent and effective. I would only use the CBD isolate if I was concerned about an upcoming drug test (full spectrum has trace amounts of THC in it)
Cristina Sanchez, a molecular biologist from Complutense University in Madrid, Spain, explains to CannaInsider, “cells, not only cancer cells, but every cell in our body can die in different ways. One could be similar to an accident, a car accident, a traumatic death which is called necrosis. And there is another way to die which is a clean death and by clean I mean no inflammation of the surrounding tissues. And this cancer cell death is called Apoptosis. And when someone’s dealing with anti-tumor compounds, one wants this particular kind of death to happen because the other one is associated to inflammatory processes and things like that that you don’t want in a patient.”
In order to convince people to buy CBD oil or other products made of hemp or containing cannabidiol, companies claim that their CBD can cure pretty much anything from cancer to acne scars, yet they have no scientific argument to back up their statements. It’s therefore not surprising to see that people are reluctant when it comes to purchasing such products, or that they feel overwhelmed and have no idea how to buy CBD oil without getting scammed.

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While researchers are calling for more robust studies on the role of CBD on mood disorders, there is promising research that points to CBD’s role as an anxiolytic – which means it has anti-anxiety effects. Another study showed CBD to have antidepressant effects comparable to those of the prescription antidepressant Imipramine. We noted above that CBD increases levels of glutamate and serotonin – and it’s these same neurotransmitters that play a crucial role in mood regulation.
Top brands that create CBD products and offer sales, grow these plants and then extract the goodness of these plants, using different techniques to produce capsules, liquids, sprays or other CBD products. There are a few different ways to extract the “goodness” from the Cannabis plants, but the method most used by all the top brands is called CO2 extraction.

The amount of milligrams of CBD you should take depends on your specific reason for taking CBD. If you are using CBD to treat chronic pain, you might take a much higher dose than someone who would be using CBD for general wellness reasons. Google search for your specific condition or reason for taking CBD to find the dose that is appropriate for you. You can take CBD in high qualities, so feel free to test out different dosages and see how your body reacts. A standard dose of CBD is 10 mg once a day, but this varies so widely because each individual is different so this can’t be taken as a recommendation for you.
The statements made regarding these products have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. Please consult your health care professional about potential interactions or other possible complications before using any product. The Federal Food, Drug and Cosmetic Act requires this notice.
Tinctures start with a raw or decarboxylated oil, but they are a more palatable (tastier if you will) option. In order to make a tincture, emulsifiers and a carrier oil and flavoring are added to the base oil. They will be packaged with a dropper or spray top for ease of use. They may even contain sweeteners. These are a great starter product or an ideal daily food supplement for anyone who does not enjoy a hempy flavor. Some flavors, like spearmint and orange, will mask the hemp flavor while other lighter options, like vanilla, will complement it.
There is a tremendous difference between CBD from hemp vs the actual cannabis plant; not addressed the fact that you are discussing CBD from hemp in the beginning of the article is confusing to those who have not been able to do their own research yet. I’ve been trying different CBD products for 2 years now & at first read, I thought you were talking about cannabis.
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